Psychotropic and MTHFR
The GeneSight Psychotropic test analyzes how your genes may affect your outcomes with medications commonly prescribed to treat depression, anxiety, ADHD, and other mental health conditions. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you or may have an increased risk of side effects based on your genetic makeup.
The GeneSight MTHFR test shows whether a person has variation in MTHFR, an enzyme required to convert folic acid and dietary folate into its active form, L-methylfolate
The GeneSight test is ordered and administered by your healthcare provider. The test is a simple cheek swab taken in your healthcare provider’s office.
The GeneSight test is ordered by your healthcare provider and sent directly to you, so you may take it in the convenience of your home. The test is a simple cheek swab, taken in your home, and returned to our lab via FedEx for processing.
The GeneSight test is administered by your healthcare provider in their office or at the comfort of your own home.
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Your provider collects a DNA sample by painlessly swabbing the inside of your cheek OR you can collect the sample at home using our patient collection kit.
The sample is sent to our lab for analysis.
After we receive your sample, your healthcare provider will typically get test results in about 2 days.
Your provider can contact our Medical Affairs team for a consultation. Your provider can then review the results with you on your next visit.
The GeneSight test report may help you avoid multiple medication trials by providing information about which medications may require dose adjustments, be less likely to work, or have an increased risk of side effects based on your genetic information.
The report also includes information on how a patient’s smoking status may affect their body’s metabolism of certain medications.
The report classifies over 60 mental health medications into four categories.
The GeneSight test results do not provide information on disease diagnosis, medication allergies, drug-drug interactions, or which medications will work best.
There are over 60 mental health medications included on the GeneSight Psychotropic test. We continuously evaluate the scientific literature and are committed to providing clinicians with genetic insights to help inform treatment decisions.
Pharmacokinetic genes tell us what the body does to the medication. These genes provide information on how a patient may break down certain medications
Pharmacodynamic genes tell us what the mediation does to the body. These genes provide information on likelihood of response and/or risk of side effects for certain medications.
These genotypes are included on the report for informational purposes only.
Our Find a Provider tool includes clinicians who are registered to offer the GeneSight test and have indicated they are now accepting new patients. Simply fill out a form to gain access to the Find a Provider tool and it will search for clinicians near you.
Understanding the GeneSight test algorithm The GeneSight test uses a unique combinatorial algorithm, which evaluates how variations in multiple genes may influence an individual’s outcomes with certain medications. The algorithm…
The GeneSight® Psychotropic test evaluates a person’s DNA to determine how they may metabolize or respond to certain medications. The GeneSight test may help inform medication selection and dosing. The…
Explore our collection of GeneSight® resources and educational materials to help you better understand what the GeneSight test can do for you.