Genetic Insights

Understanding the GeneSight test algorithm

Understanding the GeneSight test algorithm The GeneSight test uses a unique combinatorial algorithm, which evaluates how variations in multiple genes may influence an individual’s outcomes with certain medications. The algorithm…

Snapshots of Women & Depression

It is more common than you might think for women to suffer from major depressive disorder. However, depression can and should be treated. Please view this infographic to learn more…

The GeneSight^® Test & Stevens-Johnson Syndrome

By identifying the presence of the gene variations in HLA-B*1502 and HLA-A*3101, the GeneSight® Psychotropic pharmacogenomic test can predict if a patient may be at an increased risk of severe…

When All Medications are in the “Use as Directed” Column

The GeneSight Psychotropic Test and “Use as Directed” Results Sometimes, a GeneSight® Psychotropic test report will show all medications in the “Use as Directed” column. This occurs in approximately 0.7%…

Factors that May Impact Medication Response

Treating Depression How the human body responds to the medications used to treat depression is very complicated. First, there’s a lot we don’t know about depression. According to Harvard Health:…

How to Interpret the GeneSight^® Report

One of the most frequently asked questions from our patients is how to interpret the GeneSight report. The pharmacogenomic report contains a lot of useful, yet complex, information that may…

Understanding the Gene-Drug Interaction Chart

You’ve taken the GeneSight® test and have the results in hand. Your healthcare provider has likely reviewed the patient results pages with you and made recommendations on which medications may…

Evaluating the GeneSight^® Psychotropic Test

How do we know that the GeneSight® test is effective? There are multiple published studies showing the clinical validity and utility, as well as the economic utility, of the GeneSight…

Decoding Clinical Talk: Remission & Response

Read what remission means to doctors and patients.

Randomized Controlled Trials: The Gold Standard

What is a Randomized Controlled Trial (RCT)?

How Being a Poor, Intermediate, or Ultra Rapid Metabolizer can Impact Your Medication Outcomes

Two patients with depression each take the same dose of the same medication. One patient’s medication makes her feel extremely nauseous, leaves her with no energy and does not alleviate…

Pharmacogenomics: Understanding the Basics

Pharmacogenomics (phar·ma·co·ge·no·mics) may be a multisyllabic, hard-to-pronounce word. However, the relatively new field already has helped many, many people. What is Pharmacogenomics? When you go to see your healthcare provider…

Understanding the MTHFR Gene Mutation

What is MTHFR and why is it important? MTHFR is an enzyme required to convert folic acid into an active form called L-methylfolate that is usable by our bodies. L-methylfolate…

How is pharmacogenomic testing different from “traditional” diagnostic testing?

When people hear of pharmacogenomic testing, they may think it’s the same as genetic testing used to diagnose disease. The GeneSight® test is a pharmacogenomic test, not a diagnostic test.…

Am I a good candidate for GeneSight^® testing?

Am I a Good Candidate for GeneSight Testing? The GeneSight test is a genetic test that can help inform your doctor about genes that may affect how you metabolize or…