Already a registered clinic?
Take the Next Step
  1. Home
  3. Product

Product

GeneSight® Tests: Psychotropic and MTHFR

Get Started

GeneSight at Home

How It Works

Report

Find a Provider

Resources

Resources

GeneSight Psychotropic Test
MTHFR Test

The GeneSight Psychotropic Test

View Sample

The GeneSight Psychotropic Test

The GeneSight Psychotropic test analyzes how your genes may affect your outcomes with medications commonly prescribed to treat depression, anxiety, ADHD, and other mental health conditions. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you or may have an increased risk of side effects based on your genetic makeup.

The GeneSight MTHFR Test

View Sample

The GeneSight MTHFR Test

The GeneSight MTHFR test shows whether a person has variation in MTHFR, an enzyme required to convert folic acid and dietary folate into its active form, methylfolate.

How We Offer the GeneSight Test

In Clinic GeneSight Test

When we receive your sample, we review your insurance benefits to estimate your out-of-pocket cost. If it could be more than $330, we will call you before processing the test to discuss your options, including canceling the test at no cost to you.

GeneSight at Home

The GeneSight test is ordered by your healthcare provider and sent directly to you, so you may take it in the convenience of your home. The test is a simple cheek swab, taken in your home, and returned to our lab via FedEx for processing.

The GeneSight Test Process

The GeneSight test is administered by your healthcare provider in their office or at the comfort of your own home.

STEP 1

Collection

Your clinician collects a DNA sample in clinic by painlessly swabbing the inside of your cheek OR your clinician can order a patient collection kit to be sent to your home.

STEP 2

Lab

The sample is sent to our lab for analysis.

STEP 3

Results

The results are received and processed back typically within 2 business days.

STEP 4

Consultation

Results will be available from our portal and can be reviewed with the patient on their next visit. A clinician can contact our Medical Information team to review the patient's results together.

A Comprehensive Report, Personalized for You

The GeneSight Psychotropic report may help you avoid multiple medication trials by providing information about which medications may require dose adjustments, be less likely to work, or have an increased risk of side effects based on your genetic information.

The report also includes information on how a patient’s smoking status may affect their body’s metabolism of certain medications. The GeneSight results do not provide information on disease diagnosis, medication allergies, drug-drug interactions, or which medications will work best.

The report classifies over 60 mental health medications into four categories:

Use as Directed
Moderate Gene-Drug Interaction
Significant Gene-Drug Interaction
No Proven Genetic Markers

Medications on the GeneSight Psychotropic Report

There are over 60 mental health medications included on the GeneSight Psychotropic test. We continuously evaluate the scientific literature and are committed to providing clinicians with genetic insights to help inform treatment decisions.

Abilify®
(aripiprazole)

Ambien®
(zolpidem)

Anafranil®
(clomipramine)

Ativan®
(lorazepam)

Belsomra®
(suvorexant)

Buspar®
(buspirone)

Caplyta®
(lumateperone)

Celexa®
(citalopram)

Concerta®
(methyl-phenidate)

Clozaril®
(clozapine)

Cymbalta®
(duloxetine)

Dayvigo®
(lemborexant)

Depakote®
(valproic acid/divalproex)

Desyrel®
(trazodone)

Effexor XR®
(venlafaxine)

Elavil®
(amitriptyline)

Emsam®
(selegiline)

Fanapt®
(iloperidone)

Fetzima®
(levomilnacipran)

Focalin®
(dexmethyl-phenidate)

Geodon®
(ziprasidone)

Haldol®
(haloperidol)

Inderal®
(propranolol)

Intuniv®
(guanfacine)

Invega®
(paliperidone)

Klonopin®
(clonazepam)

Lamictal®
(lamotrigine)

Latuda®
(lurasidone)

Lexapro®
(escitalopram)

Librium®
(chlordiazepoxide)

Lunesta®
(eszopiclone)

Luvox®
(fluvoxamine)

Mellaril®
(thioridazine)

Navane®
(thiothixene)

Norpramin®
(desipramine)

Pamelor®
(nortriptyline)

Paxil®
(paroxetine)

Pristiq®
(desvenlafaxine)

Prolixin®
(fluphenazine)

Prozac®
(fluoxetine)

Qelbree®
(vioxazine)

Remeron®
(mirtazapine)

Restoril®
(temazepam)

Rexulti®
(brexpiprazole)

Risperdal®
(risperidone)

Ritalin®
(methyl-phenidate)

Saphris®
(asenapine)

Serax®
(oxazepam)

Seroquel®
(quetiapine)

Sinequan®
(doxepin)

Strattera®
(atomoxetine)

Tegretol®
(carbamazepine)

Thorazine®
(chlorpramazine)

Tofranil®
(imipramine)

Tranxene®
(clorazepate)

Trilafon®
(perphenazine)

Trileptal®
(oxcarbazepine)

Trintellix®
(vortioxetine)

Valium®
(diazepam)

Viibryd®
(vilazodone)

Vraylar®
(cariprazine)

Wellbutrin®
(buproprion)

Xanax®
(alprazolam)

Zoloft®
(sertraline)

Genes on the GeneSight Psychotropic Report

PK
Pharmacokinetic Genes

Pharmacokinetic genes tell us what the body does to the medication. These genes provide information on how a patient may break down certain medications.

CYP2D6
CYP2C19
CYP2C9
CYP3A4
CES1A1
CYP2B6
CYP1A2
UGT1A4
UGT2B15
PD
Pharmacodynamic Genes

Pharmacodynamic genes tell us what the medication does to the body. These genes provide information on likelihood of response and/or risk of side effects for certain medications.

SLC6A4
HLA-A*3101
ADRA2A
HTR2A
HLA-B*1502
+
Additional Genotypes

These genotypes are included on the report for informational purposes only.

COMT

Don’t Have a Clinician?
Use Our Find a Provider Tool

Our Find a Provider tool includes clinicians who are registered to offer the GeneSight test and have indicated they are now accepting new patients. Simply fill out a form to gain access to the Find a Provider tool and it will search for clinicians near you.

Educational Resources for You

Understanding the GeneSight test algorithm

Understanding the GeneSight test algorithm The GeneSight test uses a unique weighted multi-gene algorithm, which evaluates how variations in multiple genes may influence an individual’s outcomes with certain medications. The…
Read More

Resources

Explore our collection of GeneSight® resources and educational materials to help you better understand what the GeneSight test can do for you.

Read More

Educational Resources for You

Understanding the GeneSight test algorithm

Understanding the GeneSight test algorithm The GeneSight test uses a unique combinatorial algorithm, which evaluates how variations in multiple genes may influence an individual’s outcomes with certain medications. The algorithm…
Read More

Resources

Explore our collection of GeneSight® resources and educational materials to help you better understand what the GeneSight test can do for you.

Read More

Learn More about GeneSight® Testing

If you’re interested to learn more about the GeneSight test, please fill out the form below. The GeneSight test must be ordered by a registered clinician. If you are a patient/caregiver who would like your current clinician to be registered to administer the GeneSight test, please include their name and contact information.

If you are a current registered provider or tested patient, please contact us.

Please fill out the form below to take the next step.

Take the Next Step - PD

  1. Step 1
  2. Step 2
  3. Step 3
Please provide us with your name



  1. Step 1
  2. Step 2
  3. Step 3
Please provide contact and clinic information
Please provide contact information

We are asking for Date of Birth for data verification purposes.










We are asking for Date of Birth for data verification purposes.

If you do not have a clinician, we have a directory of healthcare providers who are registered to order the GeneSight test. When you complete this form, we will link you to this directory, so you will have the option to view registered GeneSight providers in your area.







Your clinician who is currently managing your medication and making treatment decisions can order your GeneSight test.

If you do not have a clinician, we have a directory of healthcare providers who are registered to order the GeneSight test. When you complete this form, we will link you to this directory, so you will have the option to view registered GeneSight providers in your area.

Please provide your clinician's information
The GeneSight test must be ordered by your clinician








  1. Step 1
  2. Step 2
  3. Step 3

How can we help?
When completed, we'll follow up with more information
Please let us know how we can best help you
When completed, we'll follow up with more information

If you are a patient or a caregiver and would like to request a copy of your results, please complete the Patient Report Request form here








Contact Information

By submitting your information in this form, you agree that your personal information may be stored and processed in any country where we have facilities or service providers, and by using our “Take the Next Step” page you agree to the possible transfer of information to countries outside of your country of residence, including to the United States, which may provide for different data protection rules than in your country. The information you submit will be utilized for the sole purpose it was submitted for and governed by our Privacy Notice.
Menu