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GeneSight® Tests: Psychotropic and MTHFR

The GeneSight Psychotropic Test

The GeneSight Psychotropic test analyzes how your genes may affect your outcomes with medications commonly prescribed to treat depression, anxiety, ADHD, and other mental health conditions. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you or may have an increased risk of side effects based on your genetic makeup.

The GeneSight Psychotropic Test

The GeneSight Psychotropic test analyzes how your genes may affect your response to medications commonly prescribed to treat depression. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you, or may have an increased risk of side effects based on your genetic makeup.

Medications on the GeneSight Psychotropic Report

Genes on the GeneSight Psychotropic Report

PK
Pharmacokinetic Genes

Pharmacokinetic genes tell us what the body does to the medication. These genes provide information on how a patient may break down certain medications.

PD
Pharmacodynamic Genes

Pharmacodynamic genes tell us what the medication does to the body. These genes provide information on likelihood of response and/or risk of side effects for certain medications.

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Additional Genotypes

These genotypes are included on the report for informational purposes only.

The GeneSight® MTHFR Test

MTHFR is an enzyme required to convert folic acid and dietary folate into its active form, which is called l-methylfolate. L-methylfolate plays an important role in making neurotransmitters, such as serotonin, dopamine, and norepinephrine, which help regulate mood. The GeneSight MTHFR test shows whether a person has variation in MTHFR, which would limit their ability to create l-methylfolate.

GeneSight Psychotropic

The GeneSight Psychotropic Test

The GeneSight Psychotropic test analyzes how your genes may affect your outcomes with medications commonly prescribed to treat depression, anxiety, ADHD, and other mental health conditions. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you or may have an increased risk of side effects based on your genetic makeup.

The GeneSight Psychotropic Test

The GeneSight Psychotropic test analyzes how your genes may affect your response to medications commonly prescribed to treat depression. The GeneSight Psychotropic test provides your clinician with information about which medications may require dose adjustments, may be less likely to work for you, or may have an increased risk of side effects based on your genetic makeup.

Medications on the GeneSight Psychotropic Report

Genes on the GeneSight Psychotropic Report

PK
Pharmacokinetic Genes

Pharmacokinetic genes tell us what the body does to the medication. These genes provide information on how a patient may break down certain medications.

PD
Pharmacodynamic Genes

Pharmacodynamic genes tell us what the medication does to the body. These genes provide information on likelihood of response and/or risk of side effects for certain medications.

+
Additional Genotypes

These genotypes are included on the report for informational purposes only.

GeneSight MTHFR

The GeneSight® MTHFR Test

MTHFR is an enzyme required to convert folic acid and dietary folate into its active form, which is called l-methylfolate. L-methylfolate plays an important role in making neurotransmitters, such as serotonin, dopamine, and norepinephrine, which help regulate mood. The GeneSight MTHFR test shows whether a person has variation in MTHFR, which would limit their ability to create l-methylfolate.

How does it work?
The GeneSight test must be ordered by your doctor or nurse practitioner. The test is a simple cheek swab taken in your healthcare provider’s office or can be sent by your doctor to be taken in the convenience of your home.

Step 1

Your doctor collects a DNA sample by painlessly swabbing the inside of your cheek OR you can collect the sample at home using our patient collection kit.

Step 2

The sample is sent to our lab for analysis.

Step 3

After we receive your sample, your doctor will typically get test results in about 2 days.

Step 4

Your doctor can contact our Medical Affairs team for a consultation. Your doctor can then review the results with you on your next visit.

How does it work?
The GeneSight test must be ordered by your doctor or nurse practitioner. The test is a simple cheek swab taken in your healthcare provider’s office or can be sent by your doctor to be taken in the convenience of your home.

Educational Resources

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