Clinical White Papers
The Pharmacogenomic (PGx) Algorithm: A common discussion among experts revolves around pharmacogenomic (PGx) testing algorithms. Many commercial tests are proprietary, and therefore, their algorithms are considered a “black box”.1 This…Read More
What is the MTHFR Polymorphism A1298C Gene Mutation, What Symptoms Should Affected Adults Look out for?
What is MTHFR? The methylenetetrahydrofolate reductase (MTHFR) enzyme converts synthetic folic acid and dietary folate into its active form, L-methylfolate, which plays a critical role in neurotransmitter synthesis. Some individuals…Read More
Introduction Pharmacogenomic reports contain a lot of useful information. Sometimes there is so much information the report can seem overwhelming. To overcome this issue and to increase the clarity of…Read More
What is the difference between traditional “single-gene” testing and the GeneSight® test’s proprietary CPGx® approach?
In multiple previous studies, the GeneSight test, a combinatorial multigene pharmacogenomic test, powered by CPGx® technology, has shown an ability to predict poorer antidepressant outcomes and to help guide healthcare…Read More