HomeBlogPatientLife Changes: Women and Depression Life Changes: Women and Depression May 28, 2020Patient Women can experience many changes throughout their lives that impact their goals, responsibilities and psyches. These life changes can be biological, like physical changes from puberty to pregnancy to menopause. One unwelcome change that may impact women through any – or all – of life’s stages could be major depressive disorder. The Mayo Clinic states that women are nearly twice as likely as men to be diagnosed with depression. The Mayo Clinic says that the higher risk of depression could be associated with hormonal changes, “other biological factors, inherited traits, and personal life circumstances and experiences.” Some major life events may put a woman at risk for depression more than others. Infertility and Depression When a woman decides to become a mother, there’s often nothing she wants more. That’s why it can be so emotionally devastating for the 12% of women in the United States who have difficulty getting pregnant. In fact, 17% of women starting reproduction treatment in a study published in Human Reproduction, were diagnosed with depression. Likewise, being infertile and the process of trying to get pregnant can have a huge psychological impact on women (and their partners). “Although the causes of infertility are overwhelmingly physiological, the resulting heartache may exact a huge psychological toll, writes Harvard Mental Health Letter. “Individuals who learn they are infertile often experience the distressing emotions common to those who are grieving a loss. Typical reactions include depression, anger, and frustration.” The medication that women take to increase their chance to become pregnant can create a variety of unwanted side effects. For example, medication prescribed to improve ovulation, may cause “anxiety, sleep interruptions, mood swings, and irritability in women,” according to Harvard Mental Health Letter. Further, “other infertility medications may cause depression, mania, irritability, and thinking problems.” An article in the North Carolina Medical Journal shares a number of additional factors that can impact mental health during infertility treatment: Financial worries – The high cost and frequency of doctors’ appointments and medical procedures can cause financial anxieties and worries about job security Self-esteem– The challenges of infertility can have a negative impact on sex life and relationships Rollercoaster of emotions – Every month that a woman gets her period and is not pregnant, she could experience a myriad of emotions: “anger, betrayal, guilt, sadness, and even hope” Physical demands– “The more physically and emotionally demanding and intrusive patients’ medical treatments become, the higher the reported symptoms of anxiety and depression.” Other people’s joy– Hearing of other’s pregnancy news or seeing pregnant women can increase a patient’s anxiety and stress. Postpartum Depression A newborn baby can change many things in a mother’s life, both physically and emotionally. Yet, not all of the changes are welcome. According to PostpartumDepression.com, in the U.S., about 1 in every 9 mothers will suffer from Postpartum Depression (PPD) sometimes called post-natal depression. Yet, the American Academy of Pediatrics estimates half of those suffering are undiagnosed and untreated. One reason mothers may experience depression after giving birth is the dramatic drop in hormones — including estrogen, progesterone, and other hormones produced by the thyroid gland after birth, The U.S. Office on Women’s Health states. During pregnancy, the production rate of these hormones hits an all-time high. Once the child is born, estrogen and progesterone dramatically decrease to normal levels within the first 24 hours. The U.S. Office on Women’s Healthlists the following symptoms of PPD: Feeling restless, moody, sad, hopeless, or overwhelmed Crying a lot or feeling worthless, guilty, or like a bad mother Having thoughts of hurting yourself or the baby Not having any interest in the baby, not feeling connected to the baby, or feeling as if your baby is someone else’s baby Having no energy or motivation Eating or sleeping too little or too much Having trouble focusing, remembering things or making decisions Losing interest or pleasure in activities you used to enjoy and/or withdrawing from friends and family Having headaches, aches and pains, or stomach problems that don’t go away “New mothers may feel embarrassed, ashamed, or guilty about feeling depressed when they are supposed to be happy,” writes the U.S. Office on Women’s Health. “Any woman can become depressed during pregnancy or after having a baby. It doesn’t mean you are a bad mom. You and your baby don’t have to suffer. There is help. Your doctor can help you figure out whether your symptoms are caused by depression or something else.” For more information about postpartum depression, read our blog post. Menopause and Depression As women enter their 40s and 50s, menopause presents another significant life change that could lead to depression. “When women go through sudden hormonal changes like those that come with perimenopause, puberty, postpartum, and even their monthly cycle, they’re at a higher risk for depression,” says Jenifer Payne, M.D., psychiatrist and director of the Women’s Mood Disorders Center at Johns Hopkins Medicine. Estrogen and progesterone are two hormones that control a woman’s menstrual cycle. These two hormones also influence serotonin, which is “a brain chemical that promotes feelings of well-being and happiness. When hormone levels drop, serotonin levels also fall, which contributes to increased irritability, anxiety and sadness,” according to Johns Hopkins Medicine. Prioritizing Mental Health During Life Changes If you suspect you’re experiencing depression during any of life’s changes, it is important to seek professional help. Talking with your doctor or specialist about your depression symptoms, medical history, and other events going on in your life could help them determine how to structure your treatment program. Women struggling with depression should also know they aren’t alone, and it’s okay to talk about how you feel with others. In addition to social media support groups, there are several online resources that help women going through similar life experiences, including: Resolve: The National Infertility Association – this group allows people to find a support group or professional in their area, in addition to support for infertility treatment, adoption, etc. Postpartum Support International – this site provides resources for mothers experiencing postpartum depression, as well as advocating for research and legislation to support perinatal mental health The North American Menopause Society – a resource for both professionals treating and women experiencing menopause, this group works to promote women’s health during menopause and beyond. For more information about depression, please visit our blog at https://genesight.com/blog. Our articles are for informational purposes only and are reviewed by our Medical Information team, which includes PharmDs, MDs, and PhDs. Do not make any changes to your current medications or dosing without consulting your healthcare provider. The GeneSight test must be ordered by and used only in consultation with a healthcare provider who can prescribe medications. As with all genetic tests, the GeneSight test results have limitations and do not constitute medical advice. The test results are designed to be just one part of a larger, complete patient assessment, which would include proper diagnosis and consideration of your medical history, other medications you may be taking, your family history, and other factors. If you are a healthcare provider and interested in learning more about the GeneSight test, please contact us at 855.891.9415. If you are a patient, please talk with your doctor to see if the GeneSight test may be helpful. Patient Hints To Help You Have A Better New Year The holidays have ended, and a new year has begun—a time when many embrace a fresh start by setting New Year’s resolutions. 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Patient Hints To Help You Have A Better New Year The holidays have ended, and a new year has begun—a time when many embrace a fresh start by setting New Year’s resolutions. This year, why not consider s... Read more
Patient Movement as Medicine: Solutions for Anxiety Moving forward. It sounds like a nice idea, especially when you’re feeling stuck deep in the throes of an anxiety spiral. But it turns out that physically m... Read more
Patient Weight-Loss Drugs and Mental Health: What You Need to Know New medications for weight loss seem to be flying off pharmacy shelves these days. But could they be linked to mental health conditions? Researchers are ... Read more
Patient 3 million patients (and counting!) have now taken the GeneSight test! We’re thrilled to share that 3 million patients (and counting!) have now taken the GeneSight test! We're so grateful to the dedicated healthcare providers who... Read more
Patient The Model Minority Myth and Mental Health The model minority myth stereotypes one cultural group, typically Asian Americans, as “intelligent, hard-working, and diligent and therefore more academically, ... Read more
Healthcare Provider How Clinicians Can Help Support Their Patients Who Are Being Bullied How Clinicians Can Help Support Their Patients Who Are Being Bullied Acts of bullying can cause feelings of fear, loneliness and sadness, as well as depressi... Read more
Patient Cyberbullying: Unique Challenges and Impacts ‘We lost our daughter to cyberbullying.’ McKenna Brown was an accomplished hockey player and scholar, known for her kindness, when she became the target of int... Read more
Going Beyond Green, Yellow, Red on the GeneSight Report This blog summarizes key points discussed during the March 2024 GeneSight® Engage webinar Participants: Bernie Ranchero, MD, MS, MBA, medical direc... Read more
Healthcare Provider Top 5 Reasons Patients Stop Their Mood Disorder Treatment Mood disorder treatment for depression can be challenging – and patients may become frustrated when treatments don’t work. In fact, when people with depres... Read more
Patient The Impact of Gratitude on Depression and Anxiety “Say ‘Thank you,” a mother reminds her young kiddo. “T.G.I.F.!” we cheer at the end of a long week. We know it’s important to be thankful. But do we ... Read more
Patient The Silent Thief: The 5 Things Depression Can Steal “Depression is a thief,” writes Abhinav Chaurasia, a marketing automation specialist in an essay on LinkedIn. “It steals your joy, your motivation, and your abi... Read more
Patient How to Talk to Your Doctor about Anxiety Medication “When I was 27, I felt bad all the time,” writes Joanna Goddard on the popular Cup of Jo blog. She describes her initial experience with anxiety in detail. ... Read more
Healthcare Provider Building Trust by Reducing Bias: The GeneSight Test as a Tool for Mental Health Equity This blog summarizes key points discussed during Myriad Mental Health’s July 2022 Webinar: Building Trust by Reducing Bias: The GeneSight Test as a Tool for Men... Read more
Patient Anxiety and older adults: What to look for and how to help “It’s not how old you are. It’s how you are, old.” - French author Jules Renard Mental health is important at every age. But when people experience an a... Read more
Patient Adult ADHD: Symptoms, treatment, where to start Many people may incorrectly think ADHD, or attention-deficit/hyperactivity disorder, only impacts children. After all, according to the Centers for Disease C... Read more
Healthcare Provider It’s time to talk suicide: addressing stigma around a difficult topic Trigger Warning: This webinar discusses suicide. If you or someone you know has suicidal thoughts, please call the National Suicide Prevention Lifeline at 988. ... Read more
Patient Stress Relief Methods for Family Caregivers Caring for a loved one can be a rewarding and meaningful experience. However, the day in and day out of taking care of someone who is unwell also can be challen... Read more
Healthcare Provider Healthcare Professional Burnout and Links to Depression When Dr. Lorna Breen, an ER doc in Manhattan, died by suicide in April 2020, it opened up a public discussion about the burdens faced by healthcare professi... Read more
Healthcare Provider Antidepressant Withdrawal or Depression Reoccurrence? What Healthcare Providers Should Know People who stop taking antidepressants may do so for many reasons: they may feel like it isn’t working, may feel unable to cope with side effects, or may not fe... Read more