HomeBlogPatientWill My Depression Treatment be Different since I’m an Older Adult? Will My Depression Treatment be Different since I’m an Older Adult? May 11, 2020Patient Growing old comes with a growing set of challenges. Your body aches. You lose friends. Kids grow up and leave home. Loved ones pass away. You grapple with loneliness. Time seems to be speeding up – and you may feel powerless to stop it. But, it’s not all bad news. According to The United States of Aging Survey, seniors are more optimistic than ever: More than 8 in 10 agree with the statement “I have a strong sense of purpose and passion about my life and my future.” Nearly two thirds of respondents (65 percent) say the past year of their life has been normal or better than normal. More than 3 in 4 seniors aged 60 to 69 expect their quality of life to stay the same or get better over the next 5 to 10 years. If 75 percent of seniors expect their quality of life to stay the same or improve, it indicates that they are not just feeling good physically – they are feeling good mentally. One way to maintain a good mental quality of life is to seek appropriate treatment for depression. Treating depression in patients 65 years and older can be different than treating younger patients. Age, the presence of other illnesses, and other medications you may be taking are three factors that your doctor may take into consideration when treating depression. Age Can Affect Medication Decisions Aging may impact how patients process certain medications. The FDA states: “As you get older, body changes can affect the way medicines are absorbed and used. For example, changes in the digestive system can affect how fast medicines enter the bloodstream. Changes in body weight can influence the amount of medicine you need to take and how long it stays in your body. The circulatory system may slow down, which can affect how fast drugs get to the liver and kidneys. The liver and kidneys also may work more slowly, affecting the way a drug breaks down and is removed from the body.” Age can also complicate genetic factors. Older patients may have impaired production of CYP450 enzymes, which can affect drug metabolism rate, according to an article published in Current Medicinal Chemistry. How Other Illnesses Can Impact Depression Treatment Aging often brings on chronic conditions – like heart disease, diabetes, and other conditions that may require medication to manage symptoms. And these conditions may bring on depression. According to the National Institute of Mental Health (NIMH), people with other chronic medical conditions have a higher risk of depression. Further, “research suggests that people who have depression and another medical illness tend to have more severe symptoms of both illnesses.” Depression shouldn’t be dismissed as just another part of illness. It can and should be treated. Talking with your doctor about your other illnesses is an important part of your treatment. “You should also inform the healthcare provider about all treatments or medications you are already receiving, including treatment for depression (prescribed medications and dietary supplements),” writes the NIMH. “Sharing information can help avoid problems with multiple medications interfering with each other. It also helps the provider stay informed about your overall health and treatment issues.” Managing Multiple Medications in Depression Treatment According to the Centers for Disease Control (CDC), 89% of older people used at least one prescription and almost 68% used three or more prescriptions within a 30 day period. Those statistics might not include over the counter (OTC) supplements or vitamins that they may be taking as well. “Many of the patients who come to see me for treatment of depression, for example, are on multiple other medicines. Cardiac medicines, medicines for pulmonary disease, medicines for pain, chronic osteoarthritis is a very common presentation for many of my patients,” said Dr. Allan Anderson, a specialist in geriatric psychiatry and past president of the American Association of Geriatric Psychiatry. “It’s uncommon for me to have any geriatric patients that come in not on any medication.” Patients are often seeing various specialists for differing ailments. As a result, since no single provider is responsible for managing the patient’s complete medication profile, drug/drug interactions could occur. This can lead to adverse drug reactions. According to an article by the American Family Physician, “adverse drug events occur in 15 percent or more of older patients presenting to offices, hospitals, and extended care facilities. These events are potentially preventable up to 50 percent of the time.” What to Expect when Talking with Your Doctor The first step in getting a depression diagnosis is scheduling an appointment with your doctor. Often, the clinician will start by using a diagnostic depression screening tool. There is a depression rating scale developed specifically for screening for depression in older adults called the Geriatric Depression Scale Short Form (GDS-SF). This 15-item screening tool typically takes 5-7 minutes to administer and asks questions like if the patient is “satisfied” with their life, if they feel their life is empty, or if they often get bored. If the doctor believes depression is present, he or she will determine an appropriate treatment, which may include talk therapy, antidepressant medication, or other therapies. For more information about the types of antidepressant medications, please read our blog post. Our articles are for informational purposes only and are reviewed by our Medical Information team, which includes PharmDs, MDs, and PhDs. Do not make any changes to your current medications or dosing without consulting your healthcare provider. The GeneSight test must be ordered by and used only in consultation with a healthcare provider who can prescribe medications. As with all genetic tests, the GeneSight test results have limitations and do not constitute medical advice. The test results are designed to be just one part of a larger, complete patient assessment, which would include proper diagnosis and consideration of your medical history, other medications you may be taking, your family history, and other factors. If you are a healthcare provider and interested in learning more about the GeneSight test, please contact us at 855.891.9415. If you are a patient, please talk with your doctor to see if the GeneSight test may be helpful. Patient BIPOC (formerly Minority) Mental Health Month: Breaking Stigma, Building Trust Despite many efforts to stem it, stigma around mental health still exists, particularly in BIPOC (Black, Indigenous, and People of Color) communities. July mark... Read more Patient Long-Term Effects of Antidepressants: What Research Shows Anyone who’s ever taken antidepressants for an extended period of time has probably wondered whether they’ll experience long-term effects: After years ... Read more Patient Have a Mindful Summer: Take a Breather with These Simple Exercises Summer is a great time to kick back and relax—if you can find the time. Managing the hustle and bustle of kids off school, planning for fun summer activities an... 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Read more Healthcare Provider Overcoming Side Effect Concerns: Leveraging Pharmacogenomic Insights to Inform Depression and Anxiety Medication Selection Whitnee Brown, a lifelong resident now practicing in Birmingham, Alabama has nearly an entire alphabet following her name, abbreviations for degrees and certifi... Read more Patient Concerns about Mental Health Medication Side Effects Remain a Barrier to Getting Help for Those Diagnosed with Depression and Anxiety Lisa Roberts has raised a family, reached an impressively high level in her career, and was an anchor for her mother and other family members. When, within ... Read more Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... Read more Patient MTHFR Mutations: Clinical Implications and Management Strategies MTHFR mutations—changes in the methylenetetrahydrofolate reductase (MTHFR) gene—have gained increased attention in the medical community due to their potent... Read more Learn more Learn more about GeneSight How to talk to your provider View our clinical studies
Patient BIPOC (formerly Minority) Mental Health Month: Breaking Stigma, Building Trust Despite many efforts to stem it, stigma around mental health still exists, particularly in BIPOC (Black, Indigenous, and People of Color) communities. July mark... Read more
Patient Long-Term Effects of Antidepressants: What Research Shows Anyone who’s ever taken antidepressants for an extended period of time has probably wondered whether they’ll experience long-term effects: After years ... Read more
Patient Have a Mindful Summer: Take a Breather with These Simple Exercises Summer is a great time to kick back and relax—if you can find the time. Managing the hustle and bustle of kids off school, planning for fun summer activities an... Read more
Patient Which Mental Health Provider Should I Consider? A Symptom-Based Guide The support of a good healthcare provider can make all the difference when you’re struggling with your mental health. But how do you connect to one in a sea of ... Read more
Patient One explanation for why we experience Side Effects? Understanding Your Genetic Response to Antidepressants Antidepressants often play an essential role in helping patients with their mental health conditions. But as many patients can attest, it’s frustrating when... Read more
Patient Barriers at Every Turn: How Systemic and Social Factors Block Men from Mental Health Care Taking the important step of seeking care for mental health isn’t always an easy decision. Uncertainty about the need for care, social stigmas associated wi... Read more
Healthcare Provider Overcoming Side Effect Concerns: Leveraging Pharmacogenomic Insights to Inform Depression and Anxiety Medication Selection Whitnee Brown, a lifelong resident now practicing in Birmingham, Alabama has nearly an entire alphabet following her name, abbreviations for degrees and certifi... Read more
Patient Concerns about Mental Health Medication Side Effects Remain a Barrier to Getting Help for Those Diagnosed with Depression and Anxiety Lisa Roberts has raised a family, reached an impressively high level in her career, and was an anchor for her mother and other family members. When, within ... Read more
Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... Read more
Patient MTHFR Mutations: Clinical Implications and Management Strategies MTHFR mutations—changes in the methylenetetrahydrofolate reductase (MTHFR) gene—have gained increased attention in the medical community due to their potent... Read more