HomeProvider StoriesGeneSight® could be the difference in months of trouble vs. months of thriving GeneSight® could be the difference in months of trouble vs. months of thriving February 20, 2024 Kyle John, MD, child psychiatristMissouri I’m a child psychiatrist with the Arc of Ozarks practice in Springfield, Missouri. We see pediatric patients for a variety of mental health issues – from autism and neurodevelopmental disabilities to general pediatric psychiatry. I was an early adopter of the GeneSight test; I’ve used it for more than 10 years. I started using it because I found the trial-and-error nature of psychiatry equivalent to throwing spaghetti at wall to see what sticks. We all want to do better than that. I don’t think of the GeneSight test as the “right drug” test. It doesn’t tell you which medication will definitely work. I think of it more like the “not the wrong drug” test. The way I use the GeneSight test is that the test helps me rule out the medications that I’m not going to try first. And it’s not just the ones in the green category. I sometimes find medications in the yellow or even red category are best suited for a patient at a lower or higher dosage because of their diagnosis and information in the clinical considerations. The GeneSight test is personal for me I’m a big believer in talk or psychotherapy before medication. Yet, my nephew had gone through two rounds of talk therapy when in high school. When he was a college freshman, his anxiety was overwhelming, and he had to move back home. When my brother asked me to prescribe something, I said, “Not without ordering the GeneSight test first.” When the GeneSight test results came back for my nephew, I realized the first couple of meds I would have prescribed may have been poor choices. It could have been the difference in months of trouble vs. months of thriving. Today, my nephew is no longer at his parent’s home debilitated by mental health challenges. He’s moved away, graduated college and he got married this summer. He is happy and healthy. And he’s no longer taking medication. So, when patients ask if I would order the GeneSight test for a family member, I share that story. Go beyond the green I tell other clinicians that the benefits of this technology are high. And significant. I tell other clinicians: “you’ve got to go beyond the green.” I’ve had times when the medication that most helps a patient is in the red zone. By using the clinical considerations, I see that I may need to use a super low dose and act accordingly. In my opinion, we should use this technology early in a child’s life because our genetics aren’t going to change. If you could know this info at two years old, someone at 20 years old may not have to struggle through multiple medications trials. Finally, I’ve found the GeneSight test helps me talk with parents who may have anxiety about putting their child on medication. Frankly, that’s good if a parent is nervous about medication – you want to do what’s best for your child and parents who are nervous ask a lot of questions about medication. So, with a GeneSight test result in hand, I can explain how I can narrow down choices to those that I think may be better tolerated. When I show them the report, a lot of times, they seem relieved and say: “OK, then we’re in.” They get a sense of confidence that it’s not going to be the trial-and-error journey they’ve had in the past. The GeneSight test is one more important piece of data that I can use to help deliver better outcomes for my patients. Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... 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Read more Patient Hints To Help You Have A Better New Year The holidays have ended, and a new year has begun—a time when many embrace a fresh start by setting New Year’s resolutions. This year, why not consider s... Read more Patient Movement as Medicine: Solutions for Anxiety Moving forward. It sounds like a nice idea, especially when you’re feeling stuck deep in the throes of an anxiety spiral. But it turns out that physically m... Read more Patient Weight-Loss Drugs and Mental Health: What You Need to Know New medications for weight loss seem to be flying off pharmacy shelves these days. But could they be linked to mental health conditions? Researchers are ... Read more Patient 3 million patients (and counting!) have now taken the GeneSight test! We’re thrilled to share that 3 million patients (and counting!) have now taken the GeneSight test! We're so grateful to the dedicated healthcare providers who... Read more Patient The Model Minority Myth and Mental Health The model minority myth stereotypes one cultural group, typically Asian Americans, as “intelligent, hard-working, and diligent and therefore more academically, ... Read more Learn more Learn more about GeneSight How to talk to your provider View our clinical studies
Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... Read more
Patient MTHFR Mutations: Clinical Implications and Management Strategies MTHFR mutations—changes in the methylenetetrahydrofolate reductase (MTHFR) gene—have gained increased attention in the medical community due to their potent... Read more
Patient Can an App Help Me Manage My Anxiety? Health and wellness smartphone apps have become so common that if you can name a health goal, desire or condition, you can probably find an app for it. N... Read more
Patient Black Trailblazers of Psychiatry and Mental Health: A Legacy of Healing and Advocacy As we celebrate Black History Month, we want to recognize a few individuals who have made extraordinary contributions to the field of psychiatry and mental heal... Read more
Patient Mindful Moments: Tips for Anxiety If a well-meaning friend or family member has ever told you to “just breathe” when you’re feeling worked up or stressed out, you’d be forgiven if you felt l... Read more
Patient Hints To Help You Have A Better New Year The holidays have ended, and a new year has begun—a time when many embrace a fresh start by setting New Year’s resolutions. This year, why not consider s... Read more
Patient Movement as Medicine: Solutions for Anxiety Moving forward. It sounds like a nice idea, especially when you’re feeling stuck deep in the throes of an anxiety spiral. But it turns out that physically m... Read more
Patient Weight-Loss Drugs and Mental Health: What You Need to Know New medications for weight loss seem to be flying off pharmacy shelves these days. But could they be linked to mental health conditions? Researchers are ... Read more
Patient 3 million patients (and counting!) have now taken the GeneSight test! We’re thrilled to share that 3 million patients (and counting!) have now taken the GeneSight test! We're so grateful to the dedicated healthcare providers who... Read more
Patient The Model Minority Myth and Mental Health The model minority myth stereotypes one cultural group, typically Asian Americans, as “intelligent, hard-working, and diligent and therefore more academically, ... Read more