Gain insight on how genetics may impact medications

Learn more about the GeneSight® test

PatientsClinicians

What is the GeneSight test?

GeneSight Psychotropic is a pharmacogenomic test which means that it analyzes how your genes may affect medication outcomes. The GeneSight test analyzes clinically important genetic variations in your DNA. Results can inform your healthcare provider about how you may break down or respond to certain medications commonly prescribed to treat depression, anxiety, ADHD, and other psychiatric conditions.

The GeneSight test must be ordered by your healthcare provider or nurse practitioner. The test is a simple cheek swab taken in your healthcare provider’s office or can be sent by your healthcare provider to be taken in the convenience of your home.


See the GeneSight test process

3,000,000+ people have taken the GeneSight test

Cost shouldn’t be a barrier

If you have insurance, we will bill your insurance for the cost of the GeneSight test. Some insurance plans will cover the cost though this can vary.

Insurance type Typical Cost
Medicare (part B) $0 out of pocket
Medicaid $0 out of pocket
Medicare advantage (part C),
commercial or other $330 or less
Uninsured $330* or less

*Reduced self-pay cost

The GeneSight Promise

If you decide to use your insurance and we determine that your cost will exceed $330, we will contact you before processing the test and before billing you to make sure you would like to proceed.

Reduced self-pay option

All patients are eligible for the reduced self-pay option of $330. Self-pay may be the most affordable option for patients whose out-of-pocket cost is estimated to be higher than $330, for those whose insurance does not cover the GeneSight test, or for those without insurance.

A comprehensive report,
personalized for you

The GeneSight test report may help you avoid multiple medication trials by providing information about which medications may require dose adjustments, be less likely to work, or have an increased risk of side effects based on your genetic information.

The report also includes information on how a patient’s smoking status may affect their body’s metabolism of certain medications.

  •  Use as directed
  •  Moderate gene-drug interaction
  •  Significant gene-drug interaction

The report classifies over 60 mental health medications into four categories.

The GeneSight test results do not provide information on disease diagnosis, medication allergies, drug-drug interactions, or which medications will work best.

Backed by extensive research

7 clinical studies published in peer-reviewed journals support the GeneSight test’s effectiveness.

GUIDED clinical study

The largest patient and rater blinded pharmacogenomic study in mental health.1

Key findings

The GeneSight test outperformed treatment as usual.

>11%

relative improvement in depressive symptoms2

>30%

relative improvement in response rates3

>50%

relative improvement in remission rates4

The GeneSight test process

The GeneSight test is administered by your healthcare provider in their office or at the comfort of your own home.

Click an icon to learn more.

Step 1

Collection

Your provider collects a DNA sample by painlessly swabbing the inside of your cheek OR you can collect the sample at home using our patient collection kit.

Step 2

Lab

The sample is sent to our lab for analysis.

Step 3

Results

After we receive your sample, your healthcare provider will typically get test results in about 2 days.

Step 4

Consultation

Your provider can contact our Medical Affairs team for a consultation. Your provider can then review the results with you on your next visit.

Step 1

Collection

Your provider collects a DNA sample by painlessly swabbing the inside of your cheek OR you can collect the sample at home using our patient collection kit.

Step 2

Lab

The sample is sent to our lab for analysis.

Step 3

Results

After we receive your sample, your healthcare provider will typically get test results in about 2 days.

Step 4

Consultation

Your provider can contact our Medical Affairs team for a consultation. Your provider can then review the results with you on your next visit.

    Hear from others
like you

    "I was so impressed with the GeneSight testing"

    Sami S., Ohio
    I’ve seen more stability and not as many side effects
    Justin, North Dakota

    "I’ve seen more stability and not as many side effects"

    Read more

    I’ve been through so much now I have hope
    Cheryl M., Utah

    "I’ve been through so much now I have hope"

    Read more

    Thank you for offering this test
    Amanda L., Ohio

    "Thank you for offering this test"

    Read more

      The stories shared on this page are individual patients’ personal experiences with GeneSight. Others may not have the same experience or outcome. Do not make any changes to your current medications or dosing without consulting your healthcare provider. The GeneSight test must be ordered by and used only in consultation with a healthcare provider who can prescribe medications.

      *Based on a review of six months of past claim data for major insurance carriers across the US. Last updated 2023.

      1. The GUIDED Clinical Study was an 8-week, blinded, randomized controlled trial of 1,167 subjects with major depressive disorder from 20 academic sites and 40 community sites.
      2. The primary endpoint of symptom improvement did not achieve statistical significance (p=0.107). Absolute improvement of 3%.
      3. Secondary endpoint of response achieved statistical significance (p=0.013). Absolute improvement of 6%
      4. Secondary endpoint of remission achieved statistical significance (p=0.007). Absolute improvement of 5%
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