HomeProvider StoriesThe GeneSight test is another tool in my toolbox The GeneSight test is another tool in my toolbox August 30, 2020 Sandra Tate, APN, CSIllinois I’m a child and adolescent psychiatric nurse practitioner. My practice serves a large geography in Southern Illinois, across the Mississippi River from St. Louis. I provide psychiatric services and medication management services in four locations and to many area residential group homes throughout the area. Many of the patients I see are children or teenagers, so their parents are very involved in treatment decisions. These decisions are not easy for parents, who have concerns about putting their child on a medication for the first time. There is a lot that is unknown, and it can be scary for them. For other parents, whose child may have tried numerous medications, it can be frustrating and discouraging to see them fail medications that are supposed to help them feel better. Any information I can give parents in this treatment process can give them peace of mind. The GeneSight Psychotropic Test Provides Insight After hearing about the GeneSight test at a medical conference five years ago, I knew it was something I wanted to learn more about. The speaker shared a pediatric case study and it really resonated with me. As I listened, I thought about how much easier it would be to have the GeneSight test results in hand when talking about medication decisions with parents. I’d have something to help me explain why I was making the treatment recommendations I was making – and it could help parents understand that I was using data and information that was specific to their child. It could give them something tangible. Now, I order the GeneSight test multiple times a week. I often see patients who have failed 2 or more medications, so ordering the test helps me understand why they may have failed in the first place. Helping a Teenager with Treatment-Resistant Depression One of the success stories I often share is about a teenager, who suffered from major depressive disorder since he was 12. The boy felt so sad and hopeless. He had taken several different antidepressants, augmented with different antipsychotics. Despite all these medication changes, he wasn’t feeling any better. After three years of trial-and-error, he was sitting in my office, sobbing and saying it was never going to get better. With his parents’ permission, I ordered the GeneSight test and I found that he had gene-drug interaction issues with most of the medications he was taking. We agreed on a revised treatment plan, which included prescribing a medication where he didn’t have gene-drug interactions. After some tweaking with dosage, my patient started to improve and became a different kid. He started doing great in school and driving. For me, this story underscores why I order the GeneSight test. Without having the information of the patient’s significant gene/drug interactions, I could have put together 100 different medication combinations. In fact, I may have never chosen that medication decision on my own. The GeneSight Test Provides Peace of Mind The GeneSight test provides something very important for my patients and their parents. They finally have a possible reason for why a medication they’ve taken hasn’t worked. It helps them understand that there might be a genetic reason they’ve failed a medication. For those patients – and their parents – they finally feel like they want to try a new treatment plan. For me, the GeneSight test is another tool in my toolbox that helps me make a good decision for my patients. The bottom line is that the GeneSight test has really helped me in my practice because it has helped me improve outcomes for my patients. Patient Which Mental Health Provider Should I Consider? A Symptom-Based Guide The support of a good healthcare provider can make all the difference when you’re struggling with your mental health. But how do you connect to one in a sea of ... Read more Patient One explanation for why we experience Side Effects? Understanding Your Genetic Response to Antidepressants Antidepressants often play an essential role in helping patients with their mental health conditions. But as many patients can attest, it’s frustrating when... Read more Patient Barriers at Every Turn: How Systemic and Social Factors Block Men from Mental Health Care Taking the important step of seeking care for mental health isn’t always an easy decision. Uncertainty about the need for care, social stigmas associated wi... Read more Healthcare Provider Overcoming Side Effect Concerns: Leveraging Pharmacogenomic Insights to Inform Depression and Anxiety Medication Selection Whitnee Brown, a lifelong resident now practicing in Birmingham, Alabama has nearly an entire alphabet following her name, abbreviations for degrees and certifi... Read more Patient Concerns about Mental Health Medication Side Effects Remain a Barrier to Getting Help for Those Diagnosed with Depression and Anxiety Lisa Roberts has raised a family, reached an impressively high level in her career, and was an anchor for her mother and other family members. When, within ... Read more Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... Read more Patient MTHFR Mutations: Clinical Implications and Management Strategies MTHFR mutations—changes in the methylenetetrahydrofolate reductase (MTHFR) gene—have gained increased attention in the medical community due to their potent... Read more Patient Can an App Help Me Manage My Anxiety? Health and wellness smartphone apps have become so common that if you can name a health goal, desire or condition, you can probably find an app for it. N... Read more Patient Black Trailblazers of Psychiatry and Mental Health: A Legacy of Healing and Advocacy As we celebrate Black History Month, we want to recognize a few individuals who have made extraordinary contributions to the field of psychiatry and mental heal... Read more Patient Mindful Moments: Tips for Anxiety If a well-meaning friend or family member has ever told you to “just breathe” when you’re feeling worked up or stressed out, you’d be forgiven if you felt l... 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Patient Which Mental Health Provider Should I Consider? A Symptom-Based Guide The support of a good healthcare provider can make all the difference when you’re struggling with your mental health. But how do you connect to one in a sea of ... Read more
Patient One explanation for why we experience Side Effects? Understanding Your Genetic Response to Antidepressants Antidepressants often play an essential role in helping patients with their mental health conditions. But as many patients can attest, it’s frustrating when... Read more
Patient Barriers at Every Turn: How Systemic and Social Factors Block Men from Mental Health Care Taking the important step of seeking care for mental health isn’t always an easy decision. Uncertainty about the need for care, social stigmas associated wi... Read more
Healthcare Provider Overcoming Side Effect Concerns: Leveraging Pharmacogenomic Insights to Inform Depression and Anxiety Medication Selection Whitnee Brown, a lifelong resident now practicing in Birmingham, Alabama has nearly an entire alphabet following her name, abbreviations for degrees and certifi... Read more
Patient Concerns about Mental Health Medication Side Effects Remain a Barrier to Getting Help for Those Diagnosed with Depression and Anxiety Lisa Roberts has raised a family, reached an impressively high level in her career, and was an anchor for her mother and other family members. When, within ... Read more
Patient Common Antidepressant Side Effects Taking an antidepressant can be an effective way to help treat a mental health condition like depression or anxiety. However, these medications can also cre... Read more
Patient MTHFR Mutations: Clinical Implications and Management Strategies MTHFR mutations—changes in the methylenetetrahydrofolate reductase (MTHFR) gene—have gained increased attention in the medical community due to their potent... Read more
Patient Can an App Help Me Manage My Anxiety? Health and wellness smartphone apps have become so common that if you can name a health goal, desire or condition, you can probably find an app for it. N... Read more
Patient Black Trailblazers of Psychiatry and Mental Health: A Legacy of Healing and Advocacy As we celebrate Black History Month, we want to recognize a few individuals who have made extraordinary contributions to the field of psychiatry and mental heal... Read more
Patient Mindful Moments: Tips for Anxiety If a well-meaning friend or family member has ever told you to “just breathe” when you’re feeling worked up or stressed out, you’d be forgiven if you felt l... Read more