Q: How do my genes affect which medication may work for me?
A: Your genes may affect the way medications work in your body—some medications could work better with your unique genetic profile and some medicines might not work well at all for you. Your genes also can affect how quickly your body breaks down (metabolizes) medicine and gets medicine into your bloodstream. For example, codeine can be an effective painkiller for some people. However, for about 10 percent of people, it has no effect whatsoever (Source: National Institutes of Health).
When a medication doesn’t work with your genes, you may not get the relief you need, and you may have additional unwanted side effects. By matching the medication to your genes, you have a much greater chance of getting on a medication that could help you.
Q: How could GeneSight help me?
A: GeneSight gives me a tool to help plan your treatment. GeneSight is designed to help me get you on the right medicine faster with fewer unwanted side effects.
GeneSight analyzes your genes and then matches the information about your genes to a list of medications that could treat your condition. The report shows which medication may work better with your genes and how your body might process those medications. That gives me additional insight to help select the medication that may work best for you.
Q: Will GeneSight work for me?
A: Pharmacogenomics is a relatively new field, but GeneSight is the only neuropsychiatric pharmacogenomics technology that is supported by multiple clinical studies published in peer-reviewed journals. In clinical testing, GeneSight is proven to double the rate of remission and response for patients versus treatment as usual. The clinical evidence is strong that it will help us find the right individualized treatment plan for you.
Q: What types of conditions can GeneSight be used for?
A: Four GeneSight test panels are available:
GeneSight Psychotropic: matching genes to medications that are FDA-approved to treat depression, anxiety, bipolar disease, schizophrenia or other neuropsychiatric conditions.
GeneSight ADHD: matching genes to medications that are FDA-approved to treat ADHD and Narcolepsy.
GeneSight Analgesic: matching genes to FDA-approved medications that can treat acute and chronic pain including opioids, NSAIDs and muscle relaxants as well as opioid dependency medications.
GeneSight MTHFR: examines how your body processes folic acid and determines if there are genetic factors which could lead to folate deficiency