HomeBlogPatientWhat Does Clinical Depression Feel Like? What Does Clinical Depression Feel Like? September 30, 2022Patient “It’s like walking through sludge.” “It took the form of contained rage.” “It’s like being trapped inside a deep, dark hole or a tiny box.” When it comes to depression, no two people have exactly the same experience. However, the above words – real descriptions of depression from people who’ve experienced it, as shared in an American Association of Retired Persons (AARP) article – begin to illustrate some of the ways it can feel. If you think you, a family member or loved one could be dealing with depression, it’s important to take those feelings seriously. Symptoms of depression “Depression (also called major depressive disorder or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working. To be diagnosed with depression, the symptoms must be present for at least two weeks,” according to the National Institute of Mental Health (NIMH). For some people with depression, symptoms build over time. For others they begin suddenly. Maria Olsen, a civil litigation attorney in Maryland with two children, experienced a depressive episode after a triggering family event. According to AARP: “‘Suddenly, I became silent and barely talked for a year – and I’m a loquacious extravert,’ Olsen says. ‘My son would cry and say, ‘Mommy, please talk!’ I just couldn’t get the words out.’ There were days when her husband would go to work and her kids to school, and she would sit and stare off into the distance until it was time to pick them up. ‘My body was there,’ she recalls, ‘but it felt like my being, my soul and my consciousness were floating overhead, watching me go through the motions. I was a ghost of myself.’” Olsen’s symptoms show how someone with depression may feel, but they are far from the only example. Some people may experience a few signs and others may feel many symptoms, according to NIMH. The website lists potential symptoms as: “Persistent sad, anxious, or ‘empty’ mood Feelings of hopelessness, or pessimism Feelings of irritability, frustration, or restlessness Feelings of guilt, worthlessness, or helplessness Loss of interest or pleasure in hobbies and activities Decreased energy, fatigue, or feeling ‘slowed down’ Difficulty concentrating, remembering, or making decisions Difficulty sleeping, early morning awakening, or oversleeping Changes in appetite or unplanned weight changes Thoughts of death or suicide, or suicide attempts Aches or pains, headaches, cramps, or digestive problems without a clear physical cause that do not ease even with treatment” For writer and radio journalist John Moe in Minnesota, depressive symptoms included anger and hopelessness. According to AARP: “As the pressures of marriage, parenthood and career built up, his depression (and anger) grew worse. He started to withdraw from friends and other close relationships. ‘My friend would call me up and say, ‘Hey, do you want to go out for beers and watch the game?’ And I would say no because I thought, ‘Well, I’m not going to be a good friend to him. … I’m gonna let him down.’ Moe’s wife finally pushed him to get help, and the psychiatrist diagnosed him with textbook depression. And with diagnosis came relief, he says. ‘It wasn’t a character flaw. It wasn’t a weakness. I’m like, Oh, I have an illness. This is something I have, not something I am.’” Seeing the point of view of someone with depression If you’ve never experienced depression before, it can be hard to imagine how overwhelming the condition can be. The symptoms can affect every aspect of a person’s life, from negatively impacting physical health to interfering with relationships with family members and friends. An immersive online experience called “How Depression Feels,” was created to offer a first-person, point-of-view tool to help others see what it can be like. It was created by the Depression and Bipolar Support Alliance (DBSA), and the makers of the GeneSight® Test, which analyzes how your genes may affect medication outcomes, including those commonly prescribed for depression. In the experience, you begin by lying in bed. As you look around your room, you see various piles of laundry and papers scattered nearby and a to-do list to accomplish. When you try to get up, examples of negative self-talk are spoken aloud, echoing how a person with depression might think to themselves: “Why bother getting up.” “Might as well just lay here for a few more hours.” “You are such a mess.” “No amount of tidying will ever change that.” As you feel your way through the experience, you can see how everyday tasks like doing laundry, taking a shower or dealing with medication can seem insurmountable for some people experiencing depression. Everyday challenges for people with depression Kate Langman saw these challenges first-hand. In her job as a stylist at Ulta Beauty, she met a customer in the hair care aisle looking for something to “fix” her hair, she tells The Mighty, but found the woman had been dealing with larger issues. “According to Langman, the woman said she had been unable to get out of bed for six months due to depression. During that time, she pulled her hair into a bun, which after months of being neglected, had matted into a ‘huge dreadlock.’” A few weeks later, over the course of eight-and-a-half hours, Langman sat down with the woman and helped her get her hair into a manageable condition. She then shared before-and-after photos on her Facebook page. “I didn’t share the post because of the transformation. I did it because I wanted people to see that depression is a real serious thing,” Langman says. Learning what depression can look like – and understanding the ways it can create everyday challenges for people experiencing it – can be an important step in connecting people to appropriate treatment when they need it. In fact, 83% of those with depression agree life would be easier if others could understand their depression, according to the GeneSight Mental Health Monitor. How is clinical depression diagnosed? If you notice that you or a friend or loved one are experiencing symptoms of depression that last more than two weeks, it may be time to reach out for help. A primary care doctor is a good first point of contact, as is a mental health professional. They’ll likely ask a series of questions and work to understand relevant medical history. According to the Cleveland Clinic: “To determine whether you have clinical depression, your healthcare provider will ask questions. You may complete a questionnaire and provide a family history. Your healthcare provider may also perform an exam or order lab tests to see if you have another medical condition.” If you’d like to search for a mental health provider near you, the Anxiety & Depression Association of America (ADAA) offers tools to help you locate a therapist. The treatment process for depression While the symptoms of depression are challenging, it’s worth keeping at it until you find help. Clinical depression, even severe depression, is treatable. “Psychotherapy and medications are the most commonly used treatments for depressive disorders,” according to the ADAA. “For mild to moderate depression, psychotherapy is generally thought to be the first line treatment. For moderate to severe depression, a combination of medications and psychotherapy is often considered.” Many patients – more than half of those diagnosed with depression – say they tried four or more depression medications in their lifetime, according to the GeneSight Mental Health Monitor. A pharmacogenomic test, like the GeneSight® test, can help inform a healthcare provider about how a patient’s genes may impact how they respond to and/or breakdown certain medications. That could include, for example, which medications may require dose adjustments, be less likely to work or have an increased risk of side effects based on a patient’s genetic makeup. The test must be ordered by a clinician who prescribes medication. Understanding suicidal depression At times, depression can feel very dark. In some cases, people with depression may even have thoughts of suicide. “Suicidal depression isn’t a clinical diagnosis, but it’s a term you may see. Instead, most mental health professionals refer to it as ‘depression with suicidal thoughts,’” according to a Healthline interview with Doreen Marshall, PhD, VP of Mission Engagement at the American Foundation for Suicide Prevention (ASFP). “When someone has clinical depression with suicidal ideation as a symptom, Marshall says it means that they are experiencing suicidal thoughts as part of their overall health symptoms. ‘However, it’s important to remember the vast majority of people who are depressed do not go on to die by suicide,’ she explains.” Yet if you are supporting a friend or family member with depression who begins to show warning signs of suicide, it’s important to get help immediately – don’t wait. The Healthline article lists potential signs as: “making statements about feeling helpless, hopeless, and worthless large changes in mood talking about wanting to die expressing no reason to go on living withdrawing from friends, family, and social interactions writing about death giving away personal items participating in excessive alcohol or drug use aggressive behavior buying a weapon or collecting and saving pills saying goodbye to friends, family, and loved ones increase in anxious or agitated behavior” It’s not too late to get help Whether you are dealing with depression yourself or are supporting someone with depression, remember that treatment can help you or your loved one get back to feeling more like yourselves again. You aren’t alone on this journey. You can take steps to feel better in time – and find better days ahead. For more information about this topic, please visit: https://genesight.com/news-and-press/only-8-of-people-remain-hopeful-after-depression-medication-fails-them-according-to-genesight-mental-health-monitor-nationwide-survey/ https://genesight.com/blog/patient/why-is-it-important-to-identify-treat-clinical-depression/ https://genesight.com/patient-stories/im-glad-that-i-asked-my-clinician-for-the-genesight-test/ Our articles are for informational purposes only and are reviewed by our Medical Information team, which includes PharmDs, MDs, and PhDs. Do not make any changes to your current medications or dosing without consulting your healthcare provider. The GeneSight test must be ordered by and used only in consultation with a healthcare provider who can prescribe medications. As with all genetic tests, the GeneSight test results have limitations and do not constitute medical advice. The test results are designed to be just one part of a larger, complete patient assessment, which would include proper diagnosis and consideration of your medical history, other medications you may be taking, your family history, and other factors. If you are a healthcare provider and interested in learning more about the GeneSight test, please contact us at 855.891.9415. If you are a patient, please talk with your doctor to see if the GeneSight test may be helpful. Patient Movement as Medicine: Solutions for Anxiety Moving forward. It sounds like a nice idea, especially when you’re feeling stuck deep in the throes of an anxiety spiral. But it turns out that physically m... Read more Patient Weight-Loss Drugs and Mental Health: What You Need to Know New medications for weight loss seem to be flying off pharmacy shelves these days. But could they be linked to mental health conditions? Researchers are ... 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What Healthcare Providers Should Know People who stop taking antidepressants may do so for many reasons: they may feel like it isn’t working, may feel unable to cope with side effects, or may not fe... Read more Learn more Learn more about GeneSight How to talk to your provider View our clinical studies
Patient Movement as Medicine: Solutions for Anxiety Moving forward. It sounds like a nice idea, especially when you’re feeling stuck deep in the throes of an anxiety spiral. But it turns out that physically m... Read more
Patient Weight-Loss Drugs and Mental Health: What You Need to Know New medications for weight loss seem to be flying off pharmacy shelves these days. But could they be linked to mental health conditions? Researchers are ... Read more
Patient 3 million patients (and counting!) have now taken the GeneSight test! We’re thrilled to share that 3 million patients (and counting!) have now taken the GeneSight test! We're so grateful to the dedicated healthcare providers who... Read more
Patient The Model Minority Myth and Mental Health The model minority myth stereotypes one cultural group, typically Asian Americans, as “intelligent, hard-working, and diligent and therefore more academically, ... Read more
Healthcare Provider How Clinicians Can Help Support Their Patients Who Are Being Bullied How Clinicians Can Help Support Their Patients Who Are Being Bullied Acts of bullying can cause feelings of fear, loneliness and sadness, as well as depressi... Read more
Patient Cyberbullying: Unique Challenges and Impacts ‘We lost our daughter to cyberbullying.’ McKenna Brown was an accomplished hockey player and scholar, known for her kindness, when she became the target of int... Read more
Going Beyond Green, Yellow, Red on the GeneSight Report This blog summarizes key points discussed during the March 2024 GeneSight® Engage webinar Participants: Bernie Ranchero, MD, MS, MBA, medical direc... Read more
Healthcare Provider Top 5 Reasons Patients Stop Their Mood Disorder Treatment Mood disorder treatment for depression can be challenging – and patients may become frustrated when treatments don’t work. In fact, when people with depres... Read more
Patient The Impact of Gratitude on Depression and Anxiety “Say ‘Thank you,” a mother reminds her young kiddo. “T.G.I.F.!” we cheer at the end of a long week. We know it’s important to be thankful. But do we ... Read more
Patient The Silent Thief: The 5 Things Depression Can Steal “Depression is a thief,” writes Abhinav Chaurasia, a marketing automation specialist in an essay on LinkedIn. “It steals your joy, your motivation, and your abi... Read more
Patient How to Talk to Your Doctor about Anxiety Medication “When I was 27, I felt bad all the time,” writes Joanna Goddard on the popular Cup of Jo blog. She describes her initial experience with anxiety in detail. ... Read more
Healthcare Provider Building Trust by Reducing Bias: The GeneSight Test as a Tool for Mental Health Equity This blog summarizes key points discussed during Myriad Mental Health’s July 2022 Webinar: Building Trust by Reducing Bias: The GeneSight Test as a Tool for Men... Read more
Patient Anxiety and older adults: What to look for and how to help “It’s not how old you are. It’s how you are, old.” - French author Jules Renard Mental health is important at every age. But when people experience an a... Read more
Patient Adult ADHD: Symptoms, treatment, where to start Many people may incorrectly think ADHD, or attention-deficit/hyperactivity disorder, only impacts children. After all, according to the Centers for Disease C... Read more
Healthcare Provider It’s time to talk suicide: addressing stigma around a difficult topic Trigger Warning: This webinar discusses suicide. If you or someone you know has suicidal thoughts, please call the National Suicide Prevention Lifeline at 988. ... Read more
Patient Stress Relief Methods for Family Caregivers Caring for a loved one can be a rewarding and meaningful experience. However, the day in and day out of taking care of someone who is unwell also can be challen... Read more
Healthcare Provider Healthcare Professional Burnout and Links to Depression When Dr. Lorna Breen, an ER doc in Manhattan, died by suicide in April 2020, it opened up a public discussion about the burdens faced by healthcare professi... Read more
Healthcare Provider Antidepressant Withdrawal or Depression Reoccurrence? What Healthcare Providers Should Know People who stop taking antidepressants may do so for many reasons: they may feel like it isn’t working, may feel unable to cope with side effects, or may not fe... Read more