HomeBlogPatientDecoding Clinical Talk: What is Depressive Disorder? Decoding Clinical Talk: What is Depressive Disorder? March 19, 2019Patient Being diagnosed with depressive disorder can be a scary moment. You may have a lot of concerns and questions. In fact, the first question may be: “What is a depressive disorder?” Several conditions fall under the “depressive disorder” umbrella. Depressive disorder is the clinical term used when reporting the severity, duration, and type of depression. According to Psychology Today, “A depressive disorder is not the same as a passing blue mood.” People with a depressive illness cannot merely ‘pull themselves together’ and get better. Without treatment, symptoms can last for weeks, months, or years. Depression is a common but serious illness, and most people who experience it need treatment to get better. Depression symptoms include loss of interest in enjoyable activities, changing sleep patterns, restlessness, feeling worthless, trouble concentrating, or thoughts of suicide. If you experience these symptoms for longer than two weeks, you may be diagnosed with a depressive disorder. Types of Depressive Disorders Major depressive disorder (MDD) is also called clinical depression. According to healthline: “MDD is one of the most common mental disorders in the United States. In 2015, nearly 7 percent of Americans over age 18 had an episode of MDD.” Persistent depressive disorder (PDD) describes an ongoing, chronic form of depression that can last for months-to-years, according to the Mayo Clinic. Sometimes called dysthymia, symptoms of PDD are similar but less severe and longer lasting than MDD. Major depression can happen for patients already experiencing persistent depression. The Mayo Clinic refers to this as “double depression.” Other forms of depressive disorder can severely impact quality of life: Seasonal affective disorder (SAD) is a form of depression that occurs during a specific time of year, typically during winter months; Psychotic depression is depression with psychotic episodes like hallucinations, delusions, or paranoia; Postpartum depression is a major depressive disorder onset in the weeks and months following childbirth; Disruptive mood dysregulation disorder is diagnosed in children and adolescents; Premenstrual dysphoric disorder (PMDD) is associated with severe depression symptoms, irritability, and tension as hormone levels fall following ovulation If you’re experiencing persistent mild, moderate, or severe symptoms of depression, or depression symptoms due to situational factors, you should seek medical help immediately. Causes of Depressive Disorder There is no single cause of depressive disorder. Biological factors, genetics, hormones, life events, etc. can all play a role. According to the National Institute of Mental Health, risk factors include: Personal or family history of depression; Major life changes, trauma, or stress; Certain physical illnesses and medications. Coping with Depressive Disorder Preventing depression can be difficult if not impossible. Several strategies can help you manage depressive symptoms. First, recognizing the signs of depression in yourself and seeking immediate help is critical. Limiting stress and talking about your mental health with family and friends can also help relieve pressure and self-doubt. Once you understand which form of depressive disorder you or a loved one are facing, you can talk with your doctor about the next steps toward treatment. There are also many self-help tips for managing depressive disorder on the GeneSight blog. Read more at https://genesight.com/blog/patient/4-ways-to-keep-your-depression-symptoms-in-check/ Our articles are for informational purposes only and are reviewed by our Medical Information team, which includes PharmDs, MDs, and PhDs. Do not make any changes to your current medications or dosing without consulting your healthcare provider. The GeneSight test must be ordered by and used only in consultation with a healthcare provider who can prescribe medications. As with all genetic tests, the GeneSight test results have limitations and do not constitute medical advice. The test results are designed to be just one part of a larger, complete patient assessment, which would include proper diagnosis and consideration of your medical history, other medications you may be taking, your family history, and other factors. If you are a healthcare provider and interested in learning more about the GeneSight test, please contact us at 855.891.9415. 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Managing the hustle and bustle of kids off school, planning for fun summer activities an... Read more Learn more Learn more about GeneSight How to talk to your provider View our clinical studies
Patient Rooting for Mental Health Heroes at the 2026 Winter Olympics The Winter Olympics has brought us unforgettable moments—Miracle on Ice, Torvill and Dean’s Bolero, the Jamaican bobsled team. They also showed heartbreak: cras... Read more
Healthcare Provider PRIME Care Time-to-Event Analysis In 2022, the United States Department of Veterans Affairs (VA) undertook the Precision Medicine in Mental Health Care, or PRIME Care study, the largest phar... Read more
Patient Healthcare Provider The GeneSight® Test: Announces New Updates As part of our ongoing commitment to ensuring that our tests evolve with the latest scientific research and clinical needs, we’ve updated the GeneSight Test. Th... Read more
Patient Is “Anxiety” on Your Playlist? “Anxiety, keep on tryin' me I feel it quietly, tryna silence me, yeah Anxiety, shake it off of me Somebody's watchin' me, it's my anxiety, yeah (Brrah) …And... Read more
Patient Break the resolution cycle: How simple solutions can transform 2026 Like every year, many of us make New Year’s resolutions and try to stick to them, but broad, all-or-nothing changes often set us up for failure and can make... Read more
Patient Antidepressant Fatigue in Seniors: A Caregiver’s Guide to Reducing Daytime Sleepiness Without Losing Symptom Control You’re spending time with the older adult in your care who also happens to have clinical depression. You’re keeping tabs on how well they’re doing and wheth... Read more
Patient Empowering Senior Patient Care with Pharmacogenomics: Insights from the GeneSight Engage Webinar The most recent GeneSight Engage webinar explored how pharmacogenomic testing, particularly the GeneSight® test, is transforming the landscape of mental health ... Read more
Patient BIPOC (formerly Minority) Mental Health Month: Breaking Stigma, Building Trust Despite many efforts to stem it, stigma around mental health still exists, particularly in BIPOC (Black, Indigenous, and People of Color) communities. July mark... Read more
Patient Long-Term Effects of Antidepressants: What Research Shows Anyone who’s ever taken antidepressants for an extended period of time has probably wondered whether they’ll experience long-term effects: After years ... Read more
Patient Have a Mindful Summer: Take a Breather with These Simple Exercises Summer is a great time to kick back and relax—if you can find the time. Managing the hustle and bustle of kids off school, planning for fun summer activities an... Read more