The GeneSight Psychotropic Test and “Use as Directed” Results

Sometimes, a GeneSight® Psychotropic test report will show all medications in the “Use as Directed” column. This occurs in approximately 0.7% of all GeneSight Psychotropic tests.

This type of result shows there is no variation found in the patient’s genes that would be expected to impact their outcomes with those medications. In other words, the patient’s phenotype is “normal” for all genes that are known to interact with a particular medication.

However, even though the category is titled “Use as Directed,” a patient may not always respond to medication listed in this category. In addition to the genes included on the GeneSight test, there are many things that can influence how your body responds to certain medications. These include drug-drug interactions, food-drug interactions, environmental factors such as lifestyle, etc.

How an all “Use as Directed” Result Can be Useful

A report that contains all medications in the “Use as Directed” column provides important clinical information for a doctor.

First, it can help “rule out” a genetic problem as the reason a patient may be failing to respond or is experiencing adverse effects to certain medications. As a result, their healthcare provider may research other reasons a medication isn’t having its desired effect (like a drug-food interaction, drug-drug interactions, other diseases the patient may have, or something else).

For some patients, this can lead to alternate approaches to treatment, such as psychotherapy or others.

For more information on how the GeneSight test can help you and your physician, visit genesight.com, email us at medinfo@myriad.com, or phone 855.891.9415.

This document is for educational purposes related to pharmacogenomics and personalized medicine only and should not be considered medical advice. The information is based on scientific opinion from industry experts and is intended to provide additional information to healthcare providers. These materials may be changed, improved, or updated without notice. Myriad Neuroscience is not responsible for any errors or omissions contained in third party content. We encourage you to contact us for specific scientific advice regarding our GeneSight® tests. You may print a copy of this document for your own personal noncommercial use. You may not copy any part of this document for any other purpose, and you may not modify any part of this document without the permission of Myriad Neuroscience. “GeneSight,” “Myriad Neuroscience” and associated logos are registered trademarks of Myriad Neuroscience. © 2020 Myriad Neuroscience. All rights reserved.